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FtsK/SpoIIIE domain-containing protein
FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids [1], termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli Swiss:P46889 and the stage III sporulation protein E SpoIIIE Swiss:P21458 which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification [1]. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer [1]. [1]. 7592387. A new Escherichia coli cell division gene, ftsK. Begg KJ, Dewar SJ, Donachie WD;. J Bacteriol 1995;177:6211-6222. [2]. 8160014. Bacillus subtilis spoIIIE protein required for DNA segregation during asymmetric cell division. Wu LJ ,Errington J;. Science 1994;264:572-575. (from Pfam)
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