The SGNH domain is named for residues Ser, Gly, Asn, and His, from four conserved regions, with the Ser and His part of the typical Ser-Acid-His catalytic triad. SGNH typically is an extracellular domain fused to a cytosolic/membrane acyltransferase-3 (AT3) carbohydrate acetyltransferase domain, which has multiple transmembrane segments.
- Date:
- 2024-08-14