Protein Family Models

This domain can be found in a group of proteins, including archaeal 6-hydroxymethylpterin diphosphokinase (6-HMDPK), known as MptE, which catalyses the formation of 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) from 6-HMD and ATP [1]. 6-HMDP is the precursor of the pterin containing moiety of the essential C1-carriers tetrahydrofolate and tetrahydromethanopterin. This entry also includes a number of uncharacterised proteins from bacteria. [1]. 22931285. Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate. de Crecy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH;. ACS Chem Biol. 2012;7:1807-1816. (from Pfam)

Date:

2024-10-16

motility associated factor (Maf) glycosyltransferase family protein involved in flagellin glycosylation, an important process in the formation of the bacterial flagellum, and in bacterial motility

Date:

2019-03-04