Protein Family Models

This bacterial domain is found at the C-terminus of Exodeoxyribonuclease I/Exonuclease I (Pfam:PF00929), which is a single-strand specific DNA nuclease affecting recombination and expression pathways. The exonuclease I protein in E. coli is associated with DNA deoxyribophosphodiesterase (dRPase) [1]. [1]. 1329027. DNA deoxyribophosphodiesterase of Escherichia coli is associated with exonuclease I. Sandigursky M, Franklin WA;. Nucleic Acids Res 1992;20:4699-4703. (from Pfam)

Date:

2024-10-16

This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III.; [1]. 8506149. RNase T shares conserved sequence motifs with DNA proofreading exonucleases. Koonin EV, Deutscher MP;. Nucleic Acids Res 1993;21:2521-2522. (from Pfam)

Date:

2024-10-16

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates

Gene:

sbcB

Date:

2023-05-09

exodeoxyribonuclease I is a monomeric enzyme that hydrolyzes single stranded DNA in the 3' to 5' direction in a highly progressive manner

Date:

2023-02-27