Protein Family Models

This domain is found in type III glutamine synthetase present in Bacteroides fragilis. Glutamine synthetase (GS) are large oligomeric enzymes that catalyze the condensation of ammonium and glutamate to form glutamine, the principal source of nitrogen for protein and nucleic acid synthesis. This domain is located in the C-terminal end of the protein [1]. [1]. 21481771. Crystal structure of Type III glutamine synthetase: surprising reversal of the inter-ring interface. van Rooyen JM, Abratt VR, Belrhali H, Sewell T;. Structure. 2011;19:471-483. (from Pfam)

Date:

2024-10-16

This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. The family is found in association with Pfam:PF00120. This family is the N terminal region of glutamine synthetase type III which is one of the enzymes responsible for generation of glutamine through conversion glutamate to glutamine by the incorporation of ammonia (NH3). [1]. 16237031. Biochemical and mutational analysis of glutamine synthetase type III from the rumen anaerobe Ruminococcus albus 8. Amaya KR, Kocherginskaya SA, Mackie RI, Cann IK;. J Bacteriol. 2005;187:7481-7491. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14