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Links from Protein

Items: 4

1.

Tyrosine--tRNA ligase SYY-like C-terminal domain

This entry represents the C-terminal domain of Tyrosine--tRNA ligases which contains the S4 motif that binds RNA [1-5]. Paper describing PDB structure 1fjg. [1]. 11014183. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Carter AP, Clemons WM, Brodersen DE, Morgan-Warren RJ, Wimberly BT, Ramakrishnan V;. Nature. 2000;407:340-348. Paper describing PDB structure 1fka. [2]. 11007480. Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution. Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A;. Cell. 2000;102:615-623. Paper describing PDB structure 1i94. [3]. 11296217. Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. Pioletti M, Schlunzen F, Harms J, Zarivach R, Gluhmann M, Avila H, Bashan A, Bartels H, Auerbach T, Jacobi C, Hartsch T, Yonath A, Franceschi F;. EMBO J. 2001;20:1829-1839. Paper describing PDB structure 1jh3. [4]. 12005430. Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase. Guijarro JI, Pintar A, Prochnicka-Chalufour A, Guez V, Gilquin B, Bedouelle H, Delepierre M;. Structure. 2002;10:311-317. Paper describing PDB structure 1jii. [5]. 11567092. Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. Qiu X, Janson CA, Smith WW, Green SM, McDevitt P, Johanson K, Carter P, Hibbs M, Lewis C, Chalker A, Fosberry A, Lalonde J, Berge J, Brown P, Houge-Frydrych CS, Jarvest RL;. Protein. TRUNCATED at 1650 bytes (from Pfam)

Date:
2024-10-16
Family Accession:
NF047180.1
Method:
HMM
2.

tRNA synthetases class I (W and Y)

GO Terms:
Molecular Function:
nucleotide binding (GO:0000166)
Molecular Function:
aminoacyl-tRNA ligase activity (GO:0004812)
Molecular Function:
ATP binding (GO:0005524)
Biological Process:
tRNA aminoacylation for protein translation (GO:0006418)
Date:
2024-08-14
Family Accession:
NF012788.5
Method:
HMM
3.

tyrosine--tRNA ligase

tyrosine--tRNA ligase catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)

Date:
2024-04-09
Family Accession:
11415010
Method:
Sparcle
4.

tyrosine--tRNA ligase

This HMM for tyrosine--tRNA ligase identifies proteins with a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples.

Gene:
tyrS
GO Terms:
Molecular Function:
nucleotide binding (GO:0000166)
Molecular Function:
tyrosine-tRNA ligase activity (GO:0004831)
Molecular Function:
ATP binding (GO:0005524)
Biological Process:
tyrosyl-tRNA aminoacylation (GO:0006437)
Date:
2024-05-15
Family Accession:
TIGR00234.1
Method:
HMM
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