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DUF1648 domain-containing protein
This domain is found in proteins expressed by bacterial or archaeal species. Some of these are annotated as being transmembrane proteins, and in fact many of these sequences contain a high proportion of hydrophobic residues. One protein containing this domain is immunity protein SdpI (swiss:O32241) from Bacillus subtilis, which provides protection for the cell against the toxic effects of its own SdpC killing factor, and also functions as a receptor/signal transduction protein [1]. [1]. 16469701. A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin. Ellermeier CD, Hobbs EC, Gonzalez-Pastor JE, Losick R;. Cell. 2006;124:549-559. (from Pfam)
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