Protein Family Models

The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function [2]. [1]. 9560229. Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis. Kovacs H, Comfort D, Lord M, Campbell ID, Yudkin MD;. Proc Natl Acad Sci U S A 1998;95:5067-5071. [2]. 10662676. The STAS domain - a link between anion transporters and antisigma-factor antagonists. Aravind L, Koonin EV;. CurrBiol 2000;10:53-55. (from Pfam)

Date:

2024-10-16

STAS (Sulphate Transporter and AntiSigma factor antagonist) domain-containing protein similar to Streptomyces coelicolor anti-sigma-B factor antagonist, a positive regulator of sigma-B activity

Date:

2024-04-18

GigB is an anti-sigma factor antagonist (an anti-anti-sigma factor) that can be dephosphorylated by GigA. In Acinetobacter baumannii, the pair coordinates the expression of genes for stress response, virulence, and antibiotic resistance.

Gene:

gigB

Date:

2018-04-18