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biotin/lipoyl-binding protein
Conserved carboxylase domain
This domain represents a conserved region in pyruvate carboxylase (PYC), oxaloacetate decarboxylase alpha chain (OADA), and transcarboxylase 5s subunit. The domain is found adjacent to the HMGL-like domain (Pfam:PF00682) and often close to the biotin_lipoyl domain (Pfam:PF00364) of biotin requiring enzymes. [1]. 9478969. Purification, regulation, and molecular and biochemical. characterization of pyruvate carboxylase from Methanobacterium. thermoautotrophicum strain deltaH.. Mukhopadhyay B, Stoddard SF, Wolfe RS;. J Biol Chem 1998;273:5155-5166. (from Pfam)
HMGL-like
This family contains a diverse set of enzymes. These include various aldolases and a region of pyruvate carboxylase. (from Pfam)
biotin/lipoyl-containing protein
This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognise the Glycine cleavage system H proteins. (from Pfam)
oxaloacetate decarboxylase subunit alpha
oxaloacetate decarboxylase subunit alpha is a component of the enzyme complex composed of three chains (alpha, beta, and gamma) that acts as a lyase and sodium transporter
Catalyzes the formation of pyruvate from oxaloacetate
pyruvate carboxylase subunit B
Catalyzes the formation of oxaloacetate from pyruvate
sodium-extruding oxaloacetate decarboxylase subunit alpha
This model describes the bacterial oxaloacetate decarboxylase alpha subunit and its equivalents in archaea. The oxaloacetate decarboxylase Na+ pump is the paradigm of the family of Na+ transport decarboxylases that present in bacteria and archaea. It a multi subunit enzyme consisting of a peripheral alpha-subunit and integral membrane subunits beta and gamma. The energy released by the decarboxylation reaction of oxaloacetate is coupled to Na+ ion pumping across the membrane.
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