Protein Family Models for Protein (Select 446075127) - Protein Family Models

Select item 4267821.

nicotinamide phosphoribosyltransferase domain-containing protein

This is the N-terminal domain found in Nicotinamide phosphoribosyltransferase (NAMPT) present in Homo sapiens. NAMPT captures nicotinamide (NAM) and replenish the nicotinamide adenine dinucleotide (NAD+) pool during ADP-ribosylation and transferase reactions [1]. [1]. 19819904. Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase. Takahashi R, Nakamura S, Nakazawa T, Minoura K, Yoshida T, Nishi Y, Kobayashi Y, Ohkubo T;. J Biochem. 2010;147:95-107. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF037045.5
Method:: HMM

Select item 4139502.

Nicotinate phosphoribosyltransferase (NAPRTase) family

Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyses the first reaction in the NAD salvage synthesis. This family also includes Pre-B cell enhancing factor that is a cytokine Swiss:P43490. This family is related to Quinolinate phosphoribosyltransferase Pfam:PF01729. [1]. 10825532. Salvage pathway for NAD biosynthesis in Brevibacterium ammoniagenes: regulatory properties of triphosphate-dependent nicotinate phosphoribosyltransferase. Dulyaninova NG, Podlepa EM, Toulokhonova1 LV, Bykhovsky VY;. Biochim Biophys Acta 2000;1478:211-220. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF016021.5
Method:: HMM

Select item 4076873.

new record, indexing in progress

Family Accession:

Select item 3913144.

new record, indexing in progress

Family Accession:

Select item 3628645.

new record, indexing in progress

Family Accession:

Select item 3507636.

new record, indexing in progress

Family Accession:

Select item 1681807.

nicotinate phosphoribosyltransferase

GO Terms:

Molecular Function:: nicotinate-nucleotide diphosphorylase (carboxylating) activity (GO:0004514)

Biological Process:: NAD biosynthetic process (GO:0009435)

Date:: 2021-08-26

Family Accession:: NF006629.0
Method:: HMM

Select item 1299258.

nicotinate phosphoribosyltransferase

nicotinate phosphoribosyltransferase (NAPRTase) catalyzes the first and rate limiting step of the NAD salvage pathway, the formation of nicotinic acid mononucleotide (NAMN) and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid

Date:: 2024-11-21

Family Accession:: 11483608
Method:: Sparcle

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