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Polysaccharide lyase family 8, N terminal alpha-helical domain
This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. [1]. 10329169. Crystal structure of chondroitin AC lyase, a representative of a family of glycosaminoglycan degrading enzymes. Fethiere J, Eggimann B, Cygler M;. J Mol Biol 1999;288:635-647. (from Pfam)
polysaccharide lyase beta-sandwich domain-containing protein
This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. [1]. 7557301. Cloning, nucleotide sequence determination and expression of the Staphylococcus aureus hyaluronate lyase gene. Farrell AM, Taylor D, Holland KT;. FEMS Microbiol Lett 1995;130:81-85. [2]. 10329169. Crystal structure of chondroitin AC lyase, a representative of a family of glycosaminoglycan degrading enzymes. Fethiere J, Eggimann B, Cygler M;. J Mol Biol 1999;288:635-647. (from Pfam)
polysaccharide lyase family 8 super-sandwich domain-containing protein
polysaccharide lyase 8 family protein
polysaccharide lyase 8 family protein similar to hyaluronate lyase that cleaves hyaluronate chains at a beta-D-GlcNAc-(1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine
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