Protein Family Models

A family based on the C-terminal domain of 3KOG which shows structural similarity to pore-forming proteins [1][2], suggesting it may have a lytic function. [1]. 15258571. Clostridium perfringens epsilon-toxin shows structural similarity to the pore-forming toxin aerolysin. Cole AR, Gibert M, Popoff M, Moss DS, Titball RW, Basak AK. Nat Struct Mol Biol. 2004 Aug;11(8):797-8. [2]. 15687495. Structural analysis of the Laetiporus sulphureus hemolytic pore-forming lectin in complex with sugars. Mancheno JM, Tateno H, Goldstein IJ, Martinez-Ripoll M, Hermoso JA. J Biol Chem. 2005 Apr 29;280(17):17251-9. (from Pfam)

Date:

2024-10-16

DUF3870 domain-containing protein may have a lytic function

Date:

2019-09-20