Protein Family Models

anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate

Date:

2024-12-04

Anhydro-N-acetylmuramic acid kinase catalyses the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. It is also required for the utilization of anhMurNAc, either imported from the medium, or derived from its own cell wall murein, and in so doing plays a role in cell wall recycling [1,2]. [1]. 15901686. Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate. Uehara T, Suefuji K, Valbuena N, Meehan B, Donegan M, Park JT;. J Bacteriol. 2005;187:3643-3649. [2]. 16452451. MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall. Uehara T, Suefuji K, Jaeger T, Mayer C, Park JT;. J Bacteriol. 2006;188:1660-1662. (from Pfam)

Date:

2024-10-16

Date:

2020-10-26

Gene:

anmK

Date:

2022-02-18