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Links from Protein

Items: 11

1.

MerR family transcriptional regulator

GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Biological Process:
regulation of DNA-templated transcription (GO:0006355)
Date:
2024-08-14
Family Accession:
NF024803.5
Method:
HMM
2.

MerR family DNA-binding protein

Members of this family of DNA-binding domains are predominantly found in the prokaryotic transcriptional regulator MerR. They adopt a structure consisting of a core of three alpha helices, with an architecture that is similar to that of the 'winged helix' fold [1]. [1]. 12958362. Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR. Changela A, Chen K, Xue Y, Holschen J, Outten CE, O'Halloran TV, Mondragon A;. Science. 2003;301:1383-1387. (from Pfam)

Date:
2024-10-16
Family Accession:
NF020839.5
Method:
HMM
3.

MerR family DNA-binding transcriptional regulator

GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Biological Process:
regulation of DNA-templated transcription (GO:0006355)
Date:
2024-08-14
Family Accession:
NF012594.5
Method:
HMM
4.
new record, indexing in progress
Family Accession:
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
Family Accession:
7.
new record, indexing in progress
Family Accession:
8.
new record, indexing in progress
Family Accession:
9.
new record, indexing in progress
Family Accession:
10.

redox-sensitive transcriptional activator SoxR

redox-sensitive transcriptional activator SoxR mediates responses to stress including exposure to heavy metals, drugs or oxygen radicals

Date:
2017-02-03
Family Accession:
11487561
Method:
Sparcle
11.

redox-sensitive transcriptional activator SoxR

SoxR is a MerR-family homodimeric transcription factor with a 2Fe-2S cluster in each monomer. The motif CIGCGCxxxxxC is conserved. Oxidation of the iron-sulfur cluster activates SoxR. The physiological role in E. coli is response to oxidative stress. It is activated by superoxide, singlet oxygen, nitric oxide (NO), and hydrogen peroxide. In E. coli, SoxR increases expression of transcription factor SoxS; different downstream targets may exist in other species.

Gene:
soxR
GO Terms:
Molecular Function:
DNA-binding transcription factor activity (GO:0003700)
Biological Process:
regulation of DNA-templated transcription (GO:0006355)
Biological Process:
response to oxidative stress (GO:0006979)
Molecular Function:
2 iron, 2 sulfur cluster binding (GO:0051537)
Date:
2024-06-27
Family Accession:
TIGR01950.1
Method:
HMM
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