Protein Family Models for Protein (Select 446341208) - Protein Family Models

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Items: 5

Select item 4109751.

alpha/beta hydrolase-fold protein

Members of this family alpha/beta hydrolase-fold proteins. Known members include hydrolases such as S-formylglutathione hydrolase (called esterase D in human) and the three paralogous mycolyltransferases of the Ag85 complex in Mycobacterium tuberculosis.

Date:: 2024-08-14

Family Accession:: NF012958.5
Method:: HMM

Select item 3885612.

new record, indexing in progress

Family Accession:

Select item 3550543.

new record, indexing in progress

Family Accession:

Select item 3475674.

new record, indexing in progress

Family Accession:

Select item 520225.

S-formylglutathione hydrolase

This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well.