Protein Family Models

This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase [1,2]. In eukaryotes it plays a role in mitochondrial complex I activity [2]. [1]. 17517780. COMPASS server for remote homology inference. Sadreyev RI, Tang M, Kim BH, Grishin NV;. Nucleic Acids Res. 2007;35:W653-W658. [2]. 20406883. MidA is a putative methyltransferase that is required for mitochondrial complex I function. Carilla-Latorre S, Gallardo ME, Annesley SJ, Calvo-Garrido J, Grana O, Accari SL, Smith PK, Valencia A, Garesse R, Fisher PR, Escalante R;. J Cell Sci. 2010;123:1674-1683. (from Pfam)

Date:

2024-10-16

class I SAM-dependent methyltransferase that catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to eukaryotic NADH dehydrogenase complex I assembly factor 7, which is involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex

Date:

2024-09-12