Protein Family Models

This domain is found in Antitoxin FitA from Neisseria gonorrhoeae and similar bacterial sequences. FitA is the antitoxin component of a type II toxin-antitoxin (TA) system. It binds DNA through its ribbon-helix-helix motif (this entry) [1]. Paper describing PDB structure 2bsq. [1]. 16982615. Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. Mattison K, Wilbur JS, So M, Brennan RG;. J Biol Chem. 2006;281:37942-37951. (from Pfam)

Date:

2024-10-21

Arc repressor act by he cooperative binding of two Arc repressor dimers to a 21-base-pair operator site. Each Arc dimer uses an antiparallel beta-sheet to recognise bases in the major groove [1]. [1]. 8107872. DNA recognition by beta-sheets in the Arc repressor-operator crystal structure. Raumann BE, Rould MA, Pabo CO, Sauer RT;. Nature 1994;367:754-757. (from Pfam)

Date:

2024-10-16

mnt family protein

Date:

2017-03-02

Date:

2019-09-10