Protein Family Models

The AIDA repeat is found on bacterial autotransporter proteins. As the repeat is short and occurs multiple times, it is likely to be the region of the transporter that acts as the stalk between the beta-barrel inserted into the membrane and the N-terminal head domain. [1]. 15547278. Novel roles for the AIDA adhesin from diarrheagenic Escherichia coli: cell aggregation and biofilm formation. Sherlock O, Schembri MA, Reisner A, Klemm P;. J Bacteriol. 2004;186:8058-8065. [2]. 15950405. Characterization and immuno-detection of AIDA-I adhesin isolated from porcine Escherichia coli. Fang Y, Ngeleka M, Middleton DM, Simko E;. Vet Microbiol. 2005;109:65-73. [3]. 1625582. AIDA-I, the adhesin involved in diffuse adherence of the diarrhoeagenic Escherichia coli strain 2787 (O126:H27), is synthesized via a precursor molecule. Benz I, Schmidt MA;. Mol Microbiol. 1992;6:1539-1546. [4]. 22466966. Discovery of an archetypal protein transport system in bacterial outer membranes. Selkrig J, Mosbahi K, Webb CT, Belousoff MJ, Perry AJ, Wells TJ, Morris F, Leyton DL, Totsika M, Phan MD, Celik N, Kelly M, Oates C, Hartland EL, Robins-Browne RM, Ramarathinam SH, Purcell AW, Schembri MA, Strugnell RA, Henderson IR, Walker D, Lithgow T;. Nat Struct Mol Biol. 2012;19:506-510. [5]. 15123066. Bugs and the gut: an unstable marriage. Farthing MJ;. Best Pract Res Clin Gastroenterol. 2004;18:233-239. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

PRK09945 family protein

Date:

2017-03-02

Date:

2020-10-26

This model describes two tandem copies of a strand-loop-strand repeat that occurs often in type V secretion system (T5SS). These repeats usually occur in the passenger domain of the classical monomeric autotransporter. Proteins with this repeat often are encoded next to a member of family TIGR04414, the Aah/TibC family O-heptosyltransferase, and may be glycosylated in regions with this repeat.

Date:

2020-10-23