Protein Family Models

These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Swiss:P50739 is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyses the cortex([1]). A similar role is carried out by the partially redundant Swiss:P42249 ([2]). It is not clear whether these enzymes are amidases or peptidases. [1]. 10658652. Complete spore-cortex hydrolysis during germination of Bacillus subtilis 168 requires SleB and YpeB. Boland FM, Atrih A, Chirakkal H, Foster SJ, Moir A;. Microbiology 2000;146:57-64. [2]. 9515903. Regulation and characterization of a newly deduced cell wall hydrolase gene (cwlJ) which affects germination of Bacillus subtilis spores. Ishikawa S, Yamane K, Sekiguchi J;. J Bacteriol 1998;180:1375-1380. (from Pfam)

Date:

2024-10-16

Gene:

cwlJ

Date:

2018-11-19

cell wall hydrolase similar to Bacillus proteins SleB and CwlJ, which are spore cortex-lytic enzymes involved in the depolymerization of cortex peptidoglycan during germination

Date:

2017-02-03