Protein Family Models

This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologues from Tn916, Tn5397, and CW459tet [1]. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length. [1]. 16788202. Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens. Bannam TL, Teng WL, Bulach D, Lyras D, Rood JI;. J Bacteriol. 2006;188:4942-4951. (from Pfam)

Date:

2024-10-16

conjugal transfer protein similar to TcpC which is required for efficient conjugal transfer; membrane localization is important for its function, as are oligomerization and interaction with the conjugation proteins TcpA, TcpH and TcpG

Date:

2016-03-29