Protein Family Models for Protein (Select 446514481) - Protein Family Models

Select item 4315821.

Family 4 Glycosyltransferase in conflict systems

This entry corresponds to Family 4 Glycosyltransferase domain comprised of two Rossmann fold subdomains. The domain is found in architecturally-rich proteins of metazoan counter-invader systems and in bacterial conflict systems [1]. [1]. 34061031. Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans. Kaur G, Iyer LM, Burroughs AM, Aravind L;. Elife. 2021; [Epub ahead of print] (from Pfam)

Date:: 2024-10-16

Family Accession:: NF045194.2
Method:: HMM

Select item 4233842.

glycosyltransferase

Date:: 2024-08-14

Family Accession:: NF025072.5
Method:: HMM

Select item 4223193.

glycosyltransferase

Date:: 2024-08-14

Family Accession:: NF024914.5
Method:: HMM

Select item 4113274.

glycosyltransferase

Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. (from Pfam)

GO Terms:

Molecular Function:: glycosyltransferase activity (GO:0016757)

Date:: 2024-08-14

Family Accession:: NF012744.5
Method:: HMM

Select item 4081755.