Protein Family Models for Protein (Select 446651017) - Protein Family Models

Select item 4310011.

Clostridial binary toxin B/anthrax toxin PA domain 3

This entry represents the beta-grasp domain in anthrax protective antigen. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF037562.5
Method:: HMM

Select item 4254642.

Clostridial binary toxin B/anthrax toxin PA domain 2

This domain forms the middle beta sandwish domain in anthrax toxin. (from Pfam)

GO Terms:

Biological Process:: protein homooligomerization (GO:0051260)

Date:: 2024-08-14

Family Accession:: NF037561.5
Method:: HMM

Select item 4175943.

PA14 domain-containing protein

This domain forms an insert in bacterial beta-glucosidases and is found in other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins, including anthrax protective antigen (PA). The domain also occurs in a Dictyostelium prespore-cell-inducing factor Psi and in fibrocystin, the mammalian protein whose mutation leads to polycystic kidney and hepatic disease. The crystal structure of PA shows that this domain (named PA14 after its location in the PA20 pro-peptide) has a beta-barrel structure. The PA14 domain sequence suggests a binding function, rather than a catalytic role. The PA14 domain distribution is compatible with carbohydrate binding. [1]. 15236739. The PA14 domain, a conserved all-beta domain in bacterial toxins, enzymes, adhesins and signaling molecules. Rigden DJ, Mello LV, Galperin MY;. Trends Biochem Sci. 2004;29:335-339. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF019311.5
Method:: HMM

Select item 4134894.

binary toxin-like calcium binding domain-containing protein

This domain is a calcium binding domain in the anthrax toxin protective antigen. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF015460.5
Method:: HMM

Select item 4056675.