Protein Family Models for Protein (Select 446689767) - Protein Family Models

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Items: 4

Select item 4167741.

RusA family crossover junction endodeoxyribonuclease

This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can resolve Holliday intermediates and correct the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC [1,2]. [1]. 8648624. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82. Mahdi AA, Sharples GJ, Mandal TN, Lloyd RG;. J Mol Biol 1996;257:561-573. [2]. 7813450. Processing of intermediates in recombination and DNA repair: identification of a new endonuclease that specifically cleaves Holliday junctions. Sharples GJ, Chan SN, Mahdi AA, Whitby MC, Lloyd RG;. EMBO J 1994;13:6133-6142. (from Pfam)

GO Terms:

Molecular Function:: magnesium ion binding (GO:0000287)

Biological Process:: DNA repair (GO:0006281)

Biological Process:: DNA recombination (GO:0006310)

Date:: 2024-10-16

Family Accession:: NF017663.5
Method:: HMM

Select item 3937312.

new record, indexing in progress

Family Accession:

Select item 3512033.

new record, indexing in progress

Family Accession:

Select item 2108444.

RusA family crossover junction endodeoxyribonuclease

RusA family crossover junction endodeoxyribonuclease similar to Lactococcus phage RusA that resolves Holliday junction intermediates and promotes DNA repair