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GHMP kinases C terminal
This family includes homoserine kinases, galactokinases and mevalonate kinases. (from Pfam)
GHMP kinases N terminal domain
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol in isoprenoid biosynthesis
Catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis
IspE (4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase) is an enzyme of the deoxyxylulose phosphate pathway (also called the non-mevalonate pathway) for isopentenyl pyrophosphate (IPP) biosynthesis. IPP is the critical building block of prenyl-derived compounds such as terpenoids.
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