Protein Family Models

This protein is plasmid encoded and found to be essential for plasmid replication [1]. [1]. 3041379. RepA protein- and oriR-dependent initiation of R1 plasmid replication: identification of a rho-dependent transcription terminator required for cis-action of repA protein. Masai H, Arai K;. Nucleic Acids Res 1988;16:6493-6514. (from Pfam)

Date:

2024-10-16

Members of this family are the plasmid replication initiator protein RepA, as the term is used in IncFII (see TIGR03474) and IncL/M plasmids. Other RepA proteins may have no readily detectable homology.

Gene:

repA

Date:

2024-05-30

Members of this protein are the plasmid replication initiator RepA of incFII (plasmid incompatibility group F-II) plasmids. R1 and R100 are plasmids in this group. Immediately upstream of repA is found tap, a leader peptide of about 24 amino acids, often not assigned as a gene in annotated plasmid sequences. Note that other, non-homologous plasmid replication proteins share the gene symbol (repA) and similar names (plasmid replication protein RepA).

Gene:

repA

Date:

2021-10-04

plasmid replication initiator protein similar to RepA of RepFIIA and RepFIIA-like replicons

Date:

2016-01-21

Date:

2020-10-26