Protein Family Models

This alpha/beta domain is found at the N-terminus of proteins such as PglD [2]. This domain binds a UDP-sugar substrate [3]. [1]. 24064219. Biochemical analysis and structure determination of bacterial acetyltransferases responsible for the biosynthesis of UDP-N,N'-diacetylbacillosamine. Morrison MJ, Imperiali B;. J Biol Chem. 2013;288:32248-32260. [2]. 18198901. Structure and active site residues of PglD, an N-acetyltransferase from the bacillosamine synthetic pathway required for N-glycan synthesis in Campylobacter jejuni. Rangarajan ES, Ruane KM, Sulea T, Watson DC, Proteau A, Leclerc S, Cygler M, Matte A, Young NM;. Biochemistry. 2008;47:1827-1836. [3]. 18667421. Crystal structure and catalytic mechanism of PglD from Campylobacter jejuni. Olivier NB, Imperiali B;. J Biol Chem. 2008;283:27937-27946. (from Pfam)

Date:

2024-10-16

acetyltransferase similar to Caulobacter vibrioides GDP-perosamine N-acetyltransferase that catalyzes the transfer of an acetyl residue from acetyl-CoA onto GDP-perosamine to form GDP-N-acetyl-perosamine; belongs to the transferase hexapeptide repeat family

Date:

2018-08-15

This family of proteins includes the characterized NeuD sialic acid O-acetyltransferase enzymes from E. coli and Streptococcus agalactiae. It also includes UDP-N-acetylbacillosamine N-acetyltransferases, GDP-perosamine N-acetyltransferases, and dTDP-4-amino-4,6-dideoxy-D-glucose acetyltransferases.

Date:

2021-09-15