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Na+/H+ antiporter NhaC family protein
This family includes integral membrane proteins, some of which are NA+/H+ antiporters [1]. [1]. 9190799. Role of the nhaC-encoded Na+/H+ antiporter of alkaliphilic Bacillus firmus OF4. Ito M, Guffanti AA, Zemsky J, Ivey DM, Krulwich TA;. J Bacteriol 1997;179:3851-3857. (from Pfam)
Na+/H+ antiporter NhaC
A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter.
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