Protein Family Models for Protein (Select 446788039) - Protein Family Models

Select item 4272781.

kelch repeat protein

Date:: 2024-08-14

Family Accession:: NF025330.5
Method:: HMM

Select item 4226782.

kelch repeat-containing protein

Date:: 2024-08-14

Family Accession:: NF024810.5
Method:: HMM

Select item 4224203.

kelch repeat-containing protein

Date:: 2024-08-14

Family Accession:: NF024807.5
Method:: HMM

Select item 4173784.

kelch repeat protein

The kelch motif was initially discovered in Kelch (Swiss:Q04652). In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase [1] for which a structure has been solved [2]. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in Pfam:PF00064, Pfam:PF00400 and Pfam:PF00415. [1]. 8126718. Drosophila kelch motif is derived from a common enzyme fold. Bork P, Doolittle RF;. J Mol Biol 1994;236:1277-1282. [2]. 2002850. Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Ito N, Phillips SE, Stevens C, Ogel ZB, McPherson MJ, Keen JN, Yadav KD, Knowles PF;. Nature 1991;350:87-90. [3]. 15475350. Crystal structure of the Kelch domain of human Keap1. Li X, Zhang D, Hannink M, Beamer LJ;. J Biol Chem 2004;279:54750-54758. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Date:: 2024-10-16

Family Accession:: NF019272.5
Method:: HMM

Select item 4135555.

kelch repeat protein

The kelch motif was initially discovered in Kelch (Swiss:Q04652). In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase [1] for which a structure has been solved [2]. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in Pfam:PF00064, Pfam:PF00400 and Pfam:PF00415. [1]. 8126718. Drosophila kelch motif is derived from a common enzyme fold. Bork P, Doolittle RF;. J Mol Biol 1994;236:1277-1282. [2]. 2002850. Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Ito N, Phillips SE, Stevens C, Ogel ZB, McPherson MJ, Keen JN, Yadav KD, Knowles PF;. Nature 1991;350:87-90. [3]. 15475350. Crystal structure of the Kelch domain of human Keap1. Li X, Zhang D, Hannink M, Beamer LJ;. J Biol Chem 2004;279:54750-54758. (from Pfam)

GO Terms:

Molecular Function:: protein binding (GO:0005515)

Date:: 2024-10-16

Family Accession:: NF013507.5
Method:: HMM

Select item 4005376.