Protein Family Models for Protein (Select 446792488) - Protein Family Models

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Items: 7

Select item 4167691.

These proteins are related to the Pfam:PF00462 family. This entry includes several viral glutaredoxins and many related bacterial and eukaryotic proteins of unknown function. The best characterised member is G4L (Swiss:P68460) from Vaccinia virus (strain Western Reserve/WR) (VACV), which is necessary for virion morphogenesis and replication [1]. This is a cytoplasmic protein which functions as a shuttle in a redox pathway between membrane-associated E10R and L1R or F9L [2]. [1]. 10982364. A glutaredoxin, encoded by the G4L gene of vaccinia virus, is essential for virion morphogenesis. White CL, Weisberg AS, Moss B;. J Virol. 2000;74:9175-9183. [2]. 11752136. Vaccinia virus G4L glutaredoxin is an essential intermediate of a cytoplasmic disulfide bond pathway required for virion assembly. White CL, Senkevich TG, Moss B;. J Virol. 2002;76:467-472. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF017574.5
Method:: HMM

Select item 4114402.

glutaredoxin domain-containing protein

GO Terms:

Molecular Function:: protein-disulfide reductase activity (GO:0015035)

Date:: 2024-08-14

Family Accession:: NF012675.5
Method:: HMM

Select item 3939703.

new record, indexing in progress

Family Accession:

Select item 3883114.

new record, indexing in progress

Family Accession:

Select item 3511475.

new record, indexing in progress

Family Accession:

Select item 3481166.

new record, indexing in progress

Family Accession:

Select item 1188017.

glutaredoxin family protein

glutaredoxin/thioredoxin family protein functions as a thiol disulfide oxidoreductase that catalyzes the oxidation or reduction of protein thiol or disulfide bonds using an active site disulfide or dithiol, present in a CXXC motif