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SH3 domain-containing protein
SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase Swiss:P12931. The structure is a partly opened beta barrel. [1]. 12169629. Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p. Kami K, Takeya R, Sumimoto H, Kohda D;. EMBO J 2002;21:4268-4276. (from Pfam)
SH3 domain-containing protein; EPS8 family SH3 and PH domain-containing protein
SH3 domain-containing protein similar to Schizosaccharomyces pombe protein csh3 and Tip elongation aberrant protein Tea4| EPS8 family SH3 (Src homology 3) and PH (Pleckstrin homology) domain-containing protein similar to SH3 and PH domains region of human EPS8, a signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture
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