Protein Family Models for Protein (Select 446848679) - Protein Family Models

Select item 4378741.

MerR family transcriptional regulator containing an N-terminal MerR family helix-turn-helix (HTH) DNA-binding domain and specific effector binding regions

Date:: 2024-11-14

Family Accession:: 18916721
Method:: Sparcle

Select item 4250732.

MerR family transcriptional regulator

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF024803.5
Method:: HMM

Select item 4155243.

GyrI-like domain-containing protein

This family contains the small molecule binding domain of a number of different bacterial transcription activators [1]. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding [3]. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira [3]. [1]. 10802742. Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Kwon HJ, Bennik MH, Demple B, Ellenberger T;. Nat Struct Biol 2000;7:424-430. [2]. 11948793. Crystal structure of the Escherichia coli SbmC protein that protects cells from the DNA replication inhibitor microcin B17. Romanowski MJ, Gibney SA, Burley SK;. Proteins 2002;47:403-407. [3]. 15281131. The SHS2 module is a common structural theme in functionally diverse protein groups, like Rpb7p, FtsA, GyrI, and MTH1598/TM1083 superfamilies. Anantharaman V, Aravind L;. Proteins. 2004;56:795-807. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF018184.5
Method:: HMM

Select item 4119904.

MerR family DNA-binding transcriptional regulator

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-08-14

Family Accession:: NF012594.5
Method:: HMM

Select item 3990775.