Protein Family Models

This family includes class II aldolases and adducins which have not been ascribed any enzymatic function. [1]. 8515438. The spatial structure of the class II L-fuculose-1-phosphate aldolase from Escherichia coli. Dreyer MK, Schulz GE;. J Mol Biol 1993;231:549-553. [2]. 8676381. Catalytic mechanism of the metal-dependent fuculose aldolase from Escherichia coli as derived from the structure. Dreyer MK, Schulz GE;. J Mol Biol 1996;259:458-466. (from Pfam)

Date:

2024-10-16

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations| L-fuculose-phosphate aldolase catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde; Also able to catalyze the reversible cleavage of D-ribulose 1-phosphate, but FucA has a higher affinity for L-fuculose 1-phosphate and L-lactaldehyde than for D-ribulose 1-phosphate and glycolaldehyde, respectively

Date:

2017-03-02

Catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate

Date:

2020-10-26