Protein Family Models

This family consists of several bacterial ferric iron reductase protein (FhuF) sequences. FhuF is involved in the reduction of ferric iron in cytoplasmic ferrioxamine B [1]. This family also includes the IucA and IucC proteins. [1]. 9990318. FhuF, an iron-regulated protein of Escherichia coli with a new type of [2Fe-2S] center. Muller K, Matzanke BF, Schunemann V, Trautwein AX, Hantke K;. Eur J Biochem 1998;258:1001-1008. (from Pfam)

Date:

2024-10-16

IucA and IucC catalyse discrete steps in biosynthesis of the siderophore aerobactin from N epsilon-acetyl-N epsilon-hydroxylysine and citrate [1]. This family represents the N-terminal region. The C-terminal region appears to be related to iron transporter proteins. [1]. 3087960. Characterization of iucA and iucC genes of the aerobactin system of plasmid ColV-K30 in Escherichia coli. de Lorenzo V, Neilands JB;. J Bacteriol 1986;167:350-355. (from Pfam)

Date:

2024-10-16

Gene:

iucC

Date:

2021-05-19

IucA/IucC family protein is a siderophore biosynthesis protein, such as the aerobactin synthase IucC, which catalyzes the attachment of the second N-acetyl-N-hydroxylysine to the carboxylic group of N-citryl-N-acetyl-N-hydroxylysine to yield aerobactin

Date:

2024-09-01

Gene:

iucC

Date:

2019-08-12