Protein Family Models

This domain is found at the N-terminal end of Secreted effector protein PipB2 from Salmonella typhimurium, which is involved in the reorganisation of late endosome/lysosome compartments in host mammalian cells. It is required for virulence. This domain a two-layer alpha-beta structure. (from Pfam)

Date:

2024-10-16

These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK [1]. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix [2]. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid. [1]. 7592418. The hglK gene is required for localization of heterocyst-specific glycolipids in the cyanobacterium Anabaena sp. strain PCC 7120. Black K, Buikema WJ, Haselkorn R;. J Bacteriol 1995;177:6440-6448. [2]. 9655353. Structure and distribution of pentapeptide repeats in bacteria. Bateman A, Murzin A, Teichmann SA;. Protein Sci 1998;7:1477-1480. [3]. 9654141. Characterisation of an Arabidopsis cDNA encoding a thylakoid lumen protein related to a novel 'pentapeptide repeat' family of proteins. Kieselbach T, Mant A, Robinson C, Schroder WP;. FEBS Lett 1998;428:241-244. (from Pfam)

Date:

2024-10-16

pentapeptide repeat-containing protein (PRP) adopts a beta-helical structure and may have a targeting or structural function

Date:

2017-03-02

Gene:

pipB

Date:

2020-10-26

Gene:

pipB

Date:

2019-11-13