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helix-turn-helix domain-containing protein
YhfZ family protein
This domain is often found in association with the helix-turn-helix domain HTH_41 (Pfam:PF14502). It includes YhfZ proteins from Escherichia coli and Shigella flexneri. (from Pfam)
GntR family transcriptional regulator YhfZ
Full-length homologs of the transcriptional regulator YhfZ from Escherichia coli, with an N-terminal GntR-like domain, are quite divergent. See PF14503 (YhfZ_C) for the broader family. This HMM identifies a subset in which the motif MPLPYxxxYEGLA and the C-terminal PxY motifs are both well conserved, suggesting orthology with conserved function.
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