Protein Family Models

Date:

2024-08-14

This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine.) These enzymes catalyse the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside. Using ATP and yielding ADP in the process. [1]. 9079672. Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2. Johansson M, Karlsson A;. J Biol Chem 1997;272:8454-8458. [2]. 8692979. Cloning and expression of human deoxyguanosine kinase cDNA. Johansson M, Karlsson A;. Proc Natl Acad Sci U S A 1996;93:7258-7262. (from Pfam)

Date:

2024-10-16

deoxynucleoside kinase catalyzes the phosphorylation of deoxyribonucleosides to yield the corresponding monophosphates

Date:

2016-05-13