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septation ring formation regulator EzrA
During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerises into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation [1]. The structure contains 5 spectrin like alpha helical repeats [2]. [1]. 10449747. Identification and characterization of a negative regulator of FtsZ ring formation in Bacillus subtilis. Levin PA, Kurtser IG, Grossman AD;. Proc Natl Acad Sci U S A 1999;96:9642-9647. Paper describing PDB structure 4uxv. [2]. 25403286. Structure and function of a spectrin-like regulator of bacterial cytokinesis. Cleverley RM, Barrett JR, Basle A, Bui NK, Hewitt L, Solovyova A, Xu ZQ, Daniel RA, Dixon NE, Harry EJ, Oakley AJ, Vollmer W, Lewis RJ;. Nat Commun. 2014;5:5421. (from Pfam)
septation ring formation regulator EzrA is a negative regulator of FtsZ ring formation; it modulates the frequency and position of FtsZ ring formation
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