This entry represents a putative component of efflux pumps that comprise MFP and FUSC proteins. Several members are in an operon with and have similar mutants phenotypes as an RND efflux pump and a fusaric acid resistance-like protein [1]. This system is involved in transporting diverse substrates including 4-hydroxybenzoate and octanoate [2]. [1]. 29769716. Mutant phenotypes for thousands of bacterial genes of unknown function. Price MN, Wetmore KM, Waters RJ, Callaghan M, Ray J, Liu H, Kuehl JV, Melnyk RA, Lamson JS, Suh Y, Carlson HK, Esquivel Z, Sadeeshkumar H, Chakraborty R, Zane GM, Rubin BE, Wall JD, Visel A, Bristow J, Blow MJ, Arkin AP, Deutschbauer AM;. Nature. 2018;557:503-509. [2]. 23774757. Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates. Skerker JM, Leon D, Price MN, Mar JS, Tarjan DR, Wetmore KM, Deutschbauer AM, Baumohl JK, Bauer S, Ibanez AB, Mitchell VD, Wu CH, Hu P, Hazen T, Arkin AP;. Mol Syst Biol. 2013;9:674. (from Pfam)
- Date:
- 2024-10-16