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type II toxin-antitoxin system RelE/ParE family toxin
ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralised by the antitoxin ParD. The family also encompasses RelE/ParE described in [2]. [1]. 1459960. Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2. Roberts RC, Helinski DR;. J Bacteriol 1992;174:8119-8132. [2]. 14659018. New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay system. Anantharaman V, Aravind L;. Genome Biol 2003;4:R81. [3]. 20487277. Interaction specificity, toxicity and regulation of a paralogous set of ParE/RelE-family toxin-antitoxin systems. Fiebig A, Castro Rojas CM, Siegal-Gaskins D, Crosson S;. Mol Microbiol. 2010;77:236-251. (from Pfam)
type II toxin-antitoxin system RelE family toxin
type II toxin-antitoxin (TA) system RelE family toxin is the RelE-like toxin component of a type II toxin-antitoxin system, its activity is attenuated by interaction with its cognate antitoxin
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