Protein Family Models

Staphopains are one of four major families of proteinases secreted by the Gram-positive Staphylococcus aureus. These staphylococcal cysteine proteases are secreted as preproenzymes that are proteolytically cleaved to generate the mature enzyme. [1]. 11767947. Molecular cloning and biochemical characterisation of proteases from Staphylococcus epidermidis. Dubin G, Chmiel D, Mak P, Rakwalska M, Rzychon M, Dubin A;. Biol Chem 2001;382:1575-1582. [2]. 11447146. Decreased amounts of cell wall-associated protein A and fibronectin-binding proteins in Staphylococcus aureus sarA mutants due to up-regulation of extracellular proteases. Karlsson A, Saravia-Otten P, Tegmark K, Morfeldt E, Arvidson S;. Infect Immun 2001;69:4742-4748. [3]. 12437090. Extracellular proteases of Staphylococcus spp. Dubin G;. Biol Chem 2002;383:1075-1086. (from Pfam)

Date:

2024-10-16