Protein Family Models for Protein (Select 488219971) - Protein Family Models

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Items: 7

Select item 4121331.

This is a family of glycine cleavage H-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. A lipoyl group is attached to a completely conserved lysine residue. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. [1]. 8197146. X-ray structure determination at 2.6-A resolution of a lipoate- containing protein: the H-protein of the glycine decarboxylase complex from pea leaves. Pares S, Cohen-Addad C, Sieker L, Neuburger M, Douce R;. Proc Natl Acad Sci U S A 1994;91:4850-4853. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF013743.5
Method:: HMM

Select item 4109982.

biotin/lipoyl-containing protein

This family covers two Prosite entries, the conserved lysine residue binds biotin in one group and lipoic acid in the other. Note that the HMM does not currently recognise the Glycine cleavage system H proteins. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012584.5
Method:: HMM

Select item 3891993.

new record, indexing in progress

Family Accession:

Select item 3890224.

new record, indexing in progress

Family Accession:

Select item 3485115.

new record, indexing in progress

Family Accession:

Select item 3469656.

new record, indexing in progress

Family Accession:

Select item 1416447.

glycine cleavage system protein H

glycine cleavage system protein H plays a role in the degradation of glycine by shuttling the methylamine group of glycine from P-protein (glycine dehydrogenase) to the T-protein (aminomethyltransferase).