Protein Family Models

This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding. (from Pfam)

Date:

2024-08-14

This DNA-binding domain is the first approx. 100 residues of the N-terminal end of Brinker. The structure of this domain in complex with DNA consists of four alpha-helices that contain a helix-turn-helix DNA recognition motif specific for GC-rich DNA. The Brinker nuclear repressor is a major element of the Drosophila Decapentaplegic morphogen signalling pathway [1]. [1]. 16876822. DNA recognition by the brinker repressor--an extreme case of coupling between binding and folding. Cordier F, Hartmann B, Rogowski M, Affolter M, Grzesiek S;. J Mol Biol. 2006;361:659-672. (from Pfam)

Date:

2024-10-16

Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family. [1]. 9180700. Genetic organization and transposition properties of IS511. D. A. Mullin, D. L. Zies, A. H. Mullin, N. Caballera & B. Ely;. Mol Gen Genet 1997;254:456-463. [2]. 8973350. The use of an improved transposon mutagenesis system for DNA sequencing leads to the characterization of a new insertion sequence of Streptomyces lividans 66. J. Fischer, H. Maier, P. Viell & J. Altenbuchner;. Gene 1996;180:81-89. [3]. 8917074. Identification and nucleotide sequence of Rhizobium meliloti insertion sequence ISRm6, a small transposable element that belongs to the IS3 family. S. Zekri & N. Toro;. Gene 1996;175:43-48. (from Pfam)

Date:

2024-10-16

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

Date:

2024-05-08

Date:

2019-09-10

Date:

2019-09-10

Date:

2019-09-10

Date:

2019-09-10