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Conserved carboxylase domain
This domain represents a conserved region in pyruvate carboxylase (PYC), oxaloacetate decarboxylase alpha chain (OADA), and transcarboxylase 5s subunit. The domain is found adjacent to the HMGL-like domain (Pfam:PF00682) and often close to the biotin_lipoyl domain (Pfam:PF00364) of biotin requiring enzymes. [1]. 9478969. Purification, regulation, and molecular and biochemical characterization of pyruvate carboxylase from Methanobacterium thermoautotrophicum strain deltaH. Mukhopadhyay B, Stoddard SF, Wolfe RS;. J Biol Chem 1998;273:5155-5166. (from Pfam)
HMGL-like
This family contains a diverse set of enzymes. These include various aldolases and a region of pyruvate carboxylase. (from Pfam)
oxaloacetate decarboxylase subunit alpha
Catalyzes the formation of pyruvate from oxaloacetate
pyruvate carboxylase subunit B
Catalyzes the formation of oxaloacetate from pyruvate
pyruvate/oxaloacetate decarboxylase subunit alpha family protein
pyruvate/oxaloacetate decarboxylase subunit alpha family protein similar to OadA, a component of the enzyme complex composed of three chains (alpha, beta, and gamma) that acts as a lyase and sodium transporter
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