Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
glycosyltransferase
The sequences scoring highest to this HMM are C-terminal regions of MurG enzymes (undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase), including the UDP-GlcNAc binding site. Those enzymes belong to glycosyltransferase family 28, but lower scoring members of this family include glycosyltransferases from other families that transfer different sugars.
The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (Swiss:P93115, EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (Swiss:P74657, EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. [1]. 1649817. The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis. Mengin-Lecreulx D, Texier L, Rousseau M, van Heijenoort J;. J Bacteriol 1991;173:4625-4636. (from Pfam)
UDP-glucoronosyl and UDP-glucosyl transferase
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase catalyzes the last step in the intracellular phase of peptidoglycan biosynthesis
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
Involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
Filter your results:
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on