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3-methyl-2-oxobutanoate hydroxymethyltransferase
Ketopantoate hydroxymethyltransferase (EC:2.1.2.11) is the first enzyme in the pantothenate biosynthesis pathway. [1]. 8096212. Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme. Jones CE, Brook JM, Buck D, Abell C, Smith AG;. J Bacteriol 1993;175:2125-2130. (from Pfam)
3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the first committed step of pantothenate (vitamin B5) synthesis.
Members of this family are 3-methyl-2-oxobutanoate hydroxymethyltransferase, the first enzyme of the pantothenate biosynthesis pathway. An alternate name is ketopantoate hydroxymethyltransferase.
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