Protein Family Models

This entry represents the transmembrane region of the 5TM-LYT (5TM Receptors of the LytS-YhcK type) [1]. [1]. 12914674. Application of comparative genomics in the identification and analysis of novel families of membrane-associated receptors in bacteria. Anantharaman V, Aravind L;. BMC Genomics 2003;4:34. (from Pfam)

Date:

2024-10-16

This family represents a region within bacterial histidine kinase enzymes. Two-component signal transduction systems such as those mediated by histidine kinase are integral parts of bacterial cellular regulatory processes, and are used to regulate the expression of genes involved in virulence [1]. Members of this family often contain Pfam:PF02518 and/or Pfam:PF00672. [1]. 12462127. Histidine kinase-mediated signal transduction systems of pathogenic microorganisms as targets for therapeutic intervention. Stephenson K, Hoch JA;. Curr Drug Targets Infect Disord 2002;2:235-246. (from Pfam)

Date:

2024-10-16

This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. [1]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu ZJ;. Proteins 2008;71:2109-13. (from Pfam)

Date:

2024-10-16

sensor histidine kinase, part of a two-component regulatory system, functions as a protein kinase that phosphorylates a target protein in response to an external signal

Date:

2024-07-10