Protein Family Models

This domain, found in various hypothetical bacterial proteins, has no known function. (from Pfam)

Date:

2024-08-14

This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase [1]. It also includes chitin deacetylase from yeast [2], and endoxylanases which hydrolyses glucosidic bonds in xylan [3]. [1]. 9163424. Molecular basis of symbiosis between Rhizobium and legumes. Freiberg C, Fellay R, Bairoch A, Broughton WJ, Rosenthal A, Perret X;. Nature 1997;387:394-401. [2]. 9133736. Cloning and expression of two chitin deacetylase genes of Saccharomyces cerevisiae. C. Mishra, C. E. Semino, K. J. McCreath, H. de la Vega, B. J. Jones, C. A. Specht & P. W. Robbins;. Yeast 1996;13:327-336. [3]. 8170399. Evidence for a general role for high-affinity non-catalytic cellulose binding domains in microbial plant cell wall hydrolases. S. J. Millward-Sadler, D. M. Poole, B. Henrissat, G. P. Hazlewood, J. H. Clarke & H. J. Gilbert;. Mol Microbiol 1994;11:375-382. (from Pfam)

Date:

2024-10-16

polysaccharide deacetylase family protein belonging to the carbohydrate esterase 4 (CE4) superfamily, may catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan; similar to Helicobacter pylori peptidoglycan deacetylase that catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection

Date:

2024-11-16