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Links from Protein

Items: 5

1.

DJ-1/PfpI family protein

The family includes the protease PfpI Swiss:Q51732 [1]. This domain is also found in transcriptional regulators such as Swiss:Q9RJG8. [1]. 8626329. Sequence, expression in Escherichia coli, and analysis of the gene encoding a novel intracellular protease (PfpI) from the hyperthermophilic archaeon Pyrococcus furiosus. Halio SB, Blumentals II, Short SA, Merrill BM, Kelly RM;. J Bacteriol 1996;178:2605-2612. [2]. 15784968. AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Ohnishi Y, Yamazaki H, Kato JY, Tomono A, Horinouchi S;. Biosci Biotechnol Biochem. 2005;69:431-439. (from Pfam)

Date:
2024-10-16
Family Accession:
NF014068.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

type 1 glutamine amidotransferase domain-containing protein

type 1 glutamine amidotransferase domain-containing protein similar to Pyrococcus furiosus deglycase PfpI that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins and reactive carbonyl groups of glyoxals (Probable)

Date:
2023-02-27
Family Accession:
10123305
Method:
Sparcle
5.

DJ-1/PfpI/YhbO family deglycase/protease

The member of this family from Pyrococcus horikoshii has been solved to 2 Angstrom resolution. It is an ATP-independent intracellular protease that crystallizes as a hexameric ring. Cys-101 is proposed as the active site residue in a catalytic triad with the adjacent His-102 and a Glu residue from an adjacent monomer. A member of this family from Bacillus subtilis, GSP18, has been shown to be expressed in response to several forms of stress. A role in the degradation of small peptides has been suggested. A closely related family consists of the thiamine biosynthesis protein ThiJ and its homologs.

GO Terms:
Biological Process:
proteolysis (GO:0006508)
Molecular Function:
cysteine-type peptidase activity (GO:0008234)
Date:
2021-04-27
Family Accession:
TIGR01382.1
Method:
HMM
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