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CopD family protein
Copper sequestering activity displayed by some bacteria is determined by copper-binding protein products of the copper resistance operon (cop). CopD, together with CopC, perform copper uptake into the cytoplasm [1]. [1]. 7917425. Molecular mechanisms of copper resistance and accumulation in bacteria. Cooksey DA;. FEMS Microbiol Rev 1994;14:381-386. (from Pfam)
CopD family protein containing a UPF0093 domain is a membrane protein that may be involved in metal ion transport
protoporphyrinogen oxidase HemJ
It appears this conserved hypothetical integral membrane protein is found only in gram negative bacteria. Completed genomes that include a member of this family include Rickettsia prowazekii, Synechocystis sp. PCC6803, and Helicobacter pylori. These proteins have 3 (Helicobacter pylori) to 5 (Synechocystis sp. PCC 6803) GES predicted transmembrane regions. Most members have 4 GES predicted transmembrane regions.
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