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aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
glutamate-1-semialdehyde 2,1-aminomutase
glutamate-1-semialdehyde 2,1-aminomutase, a pyridoxamine-5'-phosphate (PMP)/pyridoxal-5'-phosphate (PLP) dependent enzyme, catalyzes the transamination of glutamate-1-semialdehyde (GSA) to 5-aminolevulinic acid (ALA), an important step in the C5 pathway
This enzyme, glutamate-1-semialdehyde-2,1-aminomutase (glutamate-1-semialdehyde aminotransferase, GSA aminotransferase), contains a pyridoxal phosphate attached at a Lys residue at position 283 of the seed alignment. It is in the family of class III aminotransferases.
Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
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